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BioArctic’s antibody ABBV-0805 to treat Parkinson's disease receives US patent

Saturday, May 7, 2022, 15:00 Hrs  [IST]

BioArctic AB (publ) announced that the US Patent and Trademark Office (USPTO) has granted a new drug substance patent for the antibody ABBV-0805, invented by BioArctic as a potential treatment of Parkinson's disease. The patent will take effect on May 24, 2022, and expire in 2041, with the possibility of a patent term extension up until 2046.

The granted substance patent (US patent no. 11,339,212) focuses on the monoclonal antibody ABBV-0805, which selectively binds to and eliminates pathological aggregated forms called oligomers and protofibrils while sparing the physiological monomer form of alpha-synuclein. The aim is to develop a treatment that halts or slows the progression of Parkinson's disease.

At the International Congress of Parkinson's disease and movement disorders (MDS) in September 2021, results presented from the phase 1 study with ABBV-0805 supported continued development of the antibody in phase 2 with once-monthly dosing.

"We are pleased that the US Patent and Trademark Office has granted this new drug substance patent for ABBV-0805, which secures a long period of patent protection. The decision is further confirmation of the innovative nature of BioArctic's research and strengthens the protection for a potential future treatment of Parkinson’s disease in the US market," says Gunilla Osswald, CEO, BioArctic.

ABBV-0805 is a monoclonal antibody drug candidate that is designed to selectively bind and eliminate aggregated forms of alpha-synuclein such as oligomers and protofibrils, which participates in neurodegenerative disorders including Parkinson’s disease. The goal is to develop a disease modifying treatment that stops or slow down the progression of Parkinson’s disease.

BioArctic AB (publ) is a Swedish research-based biopharma company focusing on disease-modifying treatments and reliable biomarkers and diagnostics for neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease.


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