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Sinovac varicella vaccine receives prequalification from WHO

Monday, November 7, 2022, 11:00 Hrs  [IST]

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, announced that it received prequalification from the World Health Organization (WHO) for its live attenuated varicella vaccine on November 3, 2022. This marks the first WHO prequalified Chinese varicella vaccine and the fourth Sinovac vaccine to receive WHO approval.

The varicella vaccine is derived from the Oka strain and propagated in Sinovac's proprietary Human Diploid Cell (SV-1 strain), which is made by culturing and harvesting the virus, adding stabilizers and freeze-drying.

According to a phase III efficacy study, the seroconversion rate of the vaccinated children group, ages 1 to 12 years old, was 97.1%; the efficacy of the vaccine was 87.1% against varicella and 89.2% for breakthrough varicella. The vaccine provides 100% protection against moderate and severe cases.

Weidong Yin, chairman, president and CEO of Sinovac, commented, "Now that Sinovac has received WHO prequalification for our varicella vaccine, we can provide a new weapon for prevention and control of infectious diseases globally. In the future, we will continue to work on more clinical trials, registrations and approvals for vaccines worldwide, to offer the world high-quality vaccines and ensure the accessibility and affordability of these public goods."

Previously, three other vaccines by Sinovac were also approved by WHO in various uses and conditions, including Healive (the hepatitis A vaccine), CoronaVac (the Covid-19 vaccine) and the Sabin-strain inactivated polio vaccine.

Sinovac Biotech Ltd., (Sinovac) is a China-based biopharmaceutical company that focuses on the R&D, manufacturing, and commercialization of vaccines that protect against human infectious diseases.


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