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PharmaBiome, Roquette collaborate on the development of tailored fibers

Our Bureau, Bengaluru
Thursday, March 23, 2023, 16:40 Hrs  [IST]

PharmaBiome and Roquette have entered into an agreement to use the former’s proprietary technology, the NicheMap. This method allows the screening and the formulation of innovative prebiotic solutions using novel soluble fibers developed by Roquette.
At least 30 grams of fiber a day, is essential to nourish the intestinal microbiota and improve well-being. Today, fiber intake is largely below recommendation in many countries, with a foreseeable increase in different health issues such as obesity, cardiovascular diseases, diabetes and intestinal diseases in the coming years.
This deficit in fiber intake is currently called the ‘fiber gap’ and means that most people are lacking at least 10 grams of fiber per day in their diet. Fiber is an important component of a healthy diet as it promotes digestive health. It has a prebiotic effect on the gut microbiota,  reduces the risk of chronic diseases,  helps control blood sugar levels and  promotes satiety and weight management.
The use of different fibers by selective bacteria induces the production of molecules metabolites that will impact the host’s health. These fibers are qualified as prebiotics. To optimize the health benefits of a fiber, it is essential to understand how gut bacteria use their substrates and what the produced molecules are. Knowing the structural characteristics that make a prebiotic out of a fiber is key to produce new ingredients with specific health properties.
PharmaBiome is a biotech company with a deep understanding of the link between microbiome composition and function.
Dr. Tomas de Wouters, CEO of PharmaBiome, stated: "This project is an important milestone in our long-term collaboration with Roquette taking the leap from understanding the effect of fibers to using our insights to develop and optimize fiber products. Our long-standing collaboration with Roquette is a great validation of the biological relevance of our NicheMap TM technology, expanding our understanding of the microbiome and its use in the field of prebiotics.”
Backed by more than 20 years of proprietary scientific evidence in the field of soluble fibers, Roquette has developed the NUTRIOSE soluble fiber range for several years. These ingredients contribute to Page 1 of 2 selectively modulate the gut microbiota towards a healthier composition.
Dr. Laetitia Guérin-Deremaux, head of nutrition and health R&D at Roquette, said: “This project with PharmaBiome will allow Roquette to offer new microbiome-targeted fibers with scientifically proven health benefits. We are very pleased by the results of this continued collaboration which reinforces our commitment to delivering plant-based innovative ingredients to the food, nutrition and health sectors.


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