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Applied DNA Sciences, Inc., a leader in synthetic DNA manufacturing powered by scalable PCR platforms, announced it received a seventh follow-on order valued at more than $600,000 for a multi-gram quantity of LineaDNA.
The follow-on order was placed by a global manufacturer of in vitro diagnostics (IVDs) under a long-standing supply agreement for the bulk manufacture of LineaDNA used as a functional component of a cancer diagnostic test. Deliveries are scheduled across four quarterly shipments beginning in the second quarter of fiscal 2026 (ending March 31, 2026).
The LineaDNA platform is a proprietary, cell-free DNA production system leveraging Applied DNA’s deep expertise in large-scale PCR. Unlike conventional plasmid-based DNA production methods, the LineaDNA platform produces high-fidelity DNA that is free of adventitious sequences, rapidly scalable, and readily amenable to chemical modification. It can generate DNA from 100 base pairs to 20 kilobases in quantities from milligrams to grams under RUO, GLP, and GMP quality grades.
The LineaIVT platform provides a streamlined solution for mRNA production by integrating DNA IVT template manufacturing from the LineaDNA platform with the Company’s proprietary LineaRNAP enzyme. This platform’s unique integrated approach bypasses plasmid DNA as a starting material, prevents or reduces double-stranded RNA (dsRNA) contamination, and simplifies mRNA production workflows.
Applied DNA Sciences is a biotechnology company with over 20 years of experience in developing and commercializing polymerase chain reaction (PCR)-based applications for DNA production. Through its majority-owned subsidiary, LineaRx Inc., the company is commercializing its LineaDN and LineaIVT platforms to enable the manufacture of next-generation nucleic acid-based therapies.
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